2026 Mercedes-Benz C 300 (gasoline-powered compact luxury sedan): 

⛽ EPA City & Highway Fuel Economy (2026 C 300 4MATIC)

• City: ~24 mpg

• Highway: ~33 mpg

• Combined: ~27 mpg

These figures are for the all-wheel-drive (4MATIC) version, which is standard on U.S. 2026 models. 

What This Means

• City driving (stop-and-go): ~24 mpg

• Highway cruising: ~33 mpg

• Combined overall: ~27 mpg

The C 300’s 2.0 L turbocharged inline-4 engine with mild hybrid EQ Boost helps balance performance with reasonable efficiency for a compact luxury sedan. 

In some reports, the rear-wheel-drive C 300 (if available) is rated slightly higher at about 25 mpg city / 35 mpg highway, but the AWD 4MATIC figures above are the main U.S. EPA numbers most buyers will see. 

If you want real-world range estimates based on those figures and typical tank size, I can calculate that next.